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MEP1B (基因名), Meprin A subunit beta (蛋白名), mep1b_human.
产品名称:

MEP1B Antibody

货号:

P1619Rb-h

商标:
EIAab®
监管等级:
别名:

Endopeptidase-2, Meprin B, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta, PABA peptide hydrolase, PPH beta

序列号:
Q16820
反应性:
human
免疫原:
Recombinant human MEP1B protein ( R1619h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human MEP1B Polyclonal Antibody
规格 & 价格: cart
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Human MEP1B Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical staining of human liver using MEP1B antibody.
通用注释


亚单元:
Homotetramer consisting of disulfide-linked beta subunits, or heterotetramer of two alpha and two beta subunits formed by non-covalent association of two disulfide-linked heterodimers (By similarity). Interacts with MBL2 through its carbohydrate moiety. This interaction may inhibit its catalytic activity.


功能:
Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.


亚细胞位置:
Cell membrane Single-pass type I membrane protein Secreted Homodimers are essentially membrane bound but may also be shed from the surface by ADAM-10 and ADAM-17.


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