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MMP24 (基因名), Matrix metalloproteinase-24 (蛋白名), mmp24_human.
产品名称:

MMP24 Antibody

货号:

P0555Rb-h

商标:
EIAab®
监管等级:
别名:

Membrane-type matrix metalloproteinase 5, Membrane-type-5 matrix metalloproteinase, MT-MMP 5, MT5-MMP, MMP-24, MT5MMP

序列号:
Q9Y5R2
反应性:
human
免疫原:
Recombinant human MMP24 protein ( R0555h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human MMP24 Polyclonal Antibody
规格 & 价格: cart
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Human MMP24 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical analysis of formalin-fixed and paraffin embedded rat brain tissue dilution at:1:100 using MMP24 antibody.
通用注释


亚单元:
Interacts (via PDZ-binding motif) with APBA3 (via PDZ domain). Interacts with GRIP1 and GRIP2.


功能:
Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence. May play a role in axonal growth. Able to activate progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin.


亚细胞位置:
Processed matrix metalloproteinase-24 Secreted Extracellular space Extracellular matrix Also shed from cell surface as soluble proteinase, by a proteolytic cleavage.


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