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MMP2 (基因名), 72 kDa type IV collagenase (蛋白名), mmp2_human.
产品名称:

MMP2 Antibody

货号:

P0100Rb

商标:
EIAab®
监管等级:
别名:

72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, TBE-1, MMP-2, CLG4A

序列号:
P08253
反应性:
human,mouse,rat, zebrafish
免疫原:
Recombinant human MMP2 protein ( R0100h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human MMP2 Polyclonal Antibody
规格 & 价格: cart
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Human MMP2 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemistry: paraffin-embedded Human lung cancer tissue stained with anti-MMP2 antibody. Counter stained with hematoxylin.
通用注释


亚单元:
Interacts (via the C-terminal hemopexin-like domains-containing region) with the integrin alpha-V/beta-3; the interaction promotes vascular invasion in angiogenic vessels and melamoma cells. Interacts (via the C-terminal PEX domain) with TIMP2 (via the C-terminal); the interaction inhibits the degradation activity. Interacts with GSK3B.


功能:
Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.


亚细胞位置:
Isoform 2 Cytoplasm Mitochondrion


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