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NDN (基因名), Necdin (蛋白名), necd_human.
产品名称:

NDN Antibody

货号:

P0350Rb-h

商标:
EIAab®
监管等级:
序列号:
Q99608
反应性:
human
免疫原:
Recombinant human NDN protein ( R0350h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human NDN Polyclonal Antibody
规格 & 价格: cart
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Human NDN Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemistry Analysis Paraffin-embedded mouse cerebellum tissue using a 1/100 dilution of NDN Antibiody.
通用注释


亚单元:
Binds to the transactivation domains of E2F1 and p53. Binds also SV40 large T antigen and adenovirus E1A. Interacts with nucleobindin 1 and 2.


功能:
Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences.


亚细胞位置:
Perikaryon Nucleus Neural perikarya, translocates to the nucleus of postmitotic neurons and interacts with the nuclear matrix.


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