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PDGFA (基因名), Platelet-derived growth factor subunit A (蛋白名), pdgfa_human.

产品名称:

PDGFA Antibody

货号:

P0112Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

PDGF-1, Platelet-derived growth factor A chain, Platelet-derived growth factor alpha polypeptide, PDGF subunit A, PDGF1

序列号:

P04085

反应性:

human

免疫原:

corresponding to a sequence mapping at the 87-211aa of P04085

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human PDGFA Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Anti-PDGFA antibody IHC of human breast, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.

通用注释

亚单元:

Homodimer; antiparallel disulfide-linked dimer. Heterodimer with PDGFB; antiparallel disulfide-linked dimer. The PDGFA homodimer interacts with PDGFRA homodimers, and with heterodimers formed by PDGFRA and PDGFRB. The heterodimer composed of PDGFA and PDGFB interacts with PDGFRA homodimers, and with heterodimers formed by PDGFRA and PDGFRB. Interacts with CSPG4.

功能:

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB.

亚细胞位置:

Secreted Released by platelets upon wounding.

数据库链接

UniGene:

Hs.535898

SMR:

P04085

STRING:

9606.ENSP00000346508

KEGG:

hsa:5154

MIM: