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PLG (基因名), Plasminogen (蛋白名), plmn_human.
产品名称:

PLG Antibody

货号:

P1236Rb-h

商标:
EIAab®
监管等级:
序列号:
P00747
反应性:
human
免疫原:
Recombinant human PLG protein ( R1236h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human PLG Polyclonal Antibody
规格 & 价格: cart
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Human PLG Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical staining of paraffin embedded human hepatocarcinoma tissue using PLG antibody (primary antibody dilution at: 1:50).
通用注释


亚单元:
Interacts (both mature PLG and the angiostatin peptide) with CSPG4 and AMOT (PubMed:10889192, PubMed:16043488). Interacts (via the Kringle domains) with HRG; the interaction tethers PLG to the cell surface and enhances its activation (PubMed:9102401, PubMed:19712047). Interacts (via Kringle 4 domain) with ADA; the interaction stimulates PLG activation when in complex with DPP4 (PubMed:15016824). Angiostatin: Interacts with ATP5A1; the interaction inhibits most of the angiogenic effects of angiostatin (PubMed:10077593).


功能:
Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.


亚细胞位置:
Secreted Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface.


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