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PNPLA2 (基因名), Patatin-like phospholipase domain-containing protein 2 (蛋白名), plpl2_human.

产品名称:

PNPLA2 Antibody

货号:

P8796Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Adipose triglyceride lipase, Calcium-independent phospholipase A2, Desnutrin, IPLA2-zeta, Pigment epithelium-derived factor, TTS2.2, Transport-secretion protein 2, TTS2, FP17548, ATGL

序列号:

Q96AD5

反应性:

human

免疫原:

Recombinant human PNPLA2 protein ( R8796h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Cardiovascular

规格 & 价格:

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Human PNPLA2 Polyclonal Antibody

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产品说明书

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R&D 技术数据

Immunohistochemistry-Paraffin:PNPLA2 Antibody - Staining of paraffin embedded human heart. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

通用注释

亚单元:

Interacts with ABHD5; this association stimulates PNPLA2 triglyceride hydrolase activity (By similarity). Interacts with SERPINF1; interacts at one site of interaction. Despite a colocalization in lipid droplets, it probably does not interact with PLIN (By similarity). Interacts with PLIN5; prevents interaction with ABHD5 (By similarity). Interacts with FAF2 (PubMed:23297223).

功能:

Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674). Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes (PubMed:16239926). May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.

亚细胞位置:

Lipid droplet Cell membrane Single-pass type II membrane protein

数据库链接

UniGene:

Hs.654697

SMR:

Q96AD5

STRING:

9606.ENSP00000337701

KEGG:

hsa:57104

MIM: