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PMEL (基因名), Melanocyte protein PMEL (蛋白名), pmel_human.
产品名称:

PMEL Antibody

货号:

P2299Rb-h

商标:
EIAab®
监管等级:
别名:

ME20-M, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, P1, P100, Premelanosome protein, Silver locus protein homolog, ME20M, D12S53E, PMEL17, SILV

序列号:
P40967
反应性:
human
免疫原:
Recombinant human PMEL protein ( R2299h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Metabolism
Human PMEL Polyclonal Antibody
规格 & 价格: cart
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Human PMEL Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Anti-PMEL antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
通用注释


亚单元:
Heterooligomer; disulfide-linked heterooligomers of M-alpha and M-beta. Interacts with MLANA. Interacts (via luminal domain) with CD63; this is important for normal sorting of the luminal domain after proteolytic processing.


功能:
Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.


亚细胞位置:
M-alpha Secreted


该产品尚未在任何出版物中被引用。
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