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PTPN1 (基因名), Tyrosine-protein phosphatase non-receptor type 1 (蛋白名), ptn1_human.
产品名称:

PTPN1 Antibody

货号:

P1402Rb-h

商标:
EIAab®
监管等级:
别名:

Protein-tyrosine phosphatase 1B, PTP-1B, PTP1B

序列号:
P18031
反应性:
human
免疫原:
corresponding to a sequence mapping at the 2-321aa of P18031
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Epigenetics
Human PTPN1 Polyclonal Antibody
规格 & 价格: cart
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Human PTPN1 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
PTPN1 antibody detects PTPN1 protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human colon carcinoma.antibody dilution: 1:200.
通用注释


亚单元:
Interacts with EPHA3 (phosphorylated); dephosphorylates EPHA3 and may regulate its trafficking and function. Interacts with MET.


功能:
Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.


亚细胞位置:
Endoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic side Interacts with EPHA3 at the cell membrane.


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