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PTPRC (基因名), Receptor-type tyrosine-protein phosphatase C (蛋白名), ptprc_human.
产品名称:

PTPRC Antibody

货号:

P1030Rb-h

商标:
EIAab®
监管等级:
别名:

Leukocyte common antigen, T200, L-CA, CD45, CD45

序列号:
P08575
反应性:
human
免疫原:
Recombinant human PTPRC protein ( R1030h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human PTPRC Polyclonal Antibody
规格 & 价格: cart
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Human PTPRC Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical of paraffin-embedded human lymphoma using PTPRC antibody at dilution of 1:20.?
通用注释


亚单元:
Binds GANAB and PRKCSH (By similarity). Interacts with SKAP1. Interacts with DPP4; the interaction is enhanced in a interleukin-12-dependent manner in activated lymphocytes. Interacts with human cytomegalovirus protein UL11.


功能:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.


亚细胞位置:
Membrane Single-pass type I membrane protein Membrane raft Colocalized with DPP4 in membrane rafts.


该产品尚未在任何出版物中被引用。
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