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PWWP3A (基因名), PWWP domain-containing DNA repair factor 3A (蛋白名), pwp3a_human.
产品名称:

PWWP3A Antibody

货号:

P1142Rb-h

商标:
EIAab®
监管等级:
别名:

Mutated melanoma-associated antigen 1, PWWP domain-containing protein MUM1, Protein expandere, MUM-1, PWWP3A, EXPAND1, MUM1

序列号:
Q2TAK8
反应性:
human
免疫原:
Recombinant human PWWP3A protein ( R1142h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cell Biology
Human PWWP3A Polyclonal Antibody
规格 & 价格: cart
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Human PWWP3A Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical staining of MUM1 in human heart muscle shows distinct staining of intercalated disc in myocytes. Samples were probed using a MUM1 Polyclonal Antibody.
通用注释


亚单元:
Interacts with TP53BP1 (via BRCT domain); the interaction is not dependent on its phosphorylation status. Binds nucleosomes. Interacts with trimethylated 'Lys-36' of histone H3 (H3K36me3) (in vitro).


功能:
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.


亚细胞位置:
Nucleus Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.


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