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RAB14 (基因名), Ras-related protein Rab-14 (蛋白名), rab14_human.

产品名称:

RAB14 Antibody

货号:

P14990Rb

商标:

EIAab^®

监管等级:

RUO

序列号:

P61106

反应性:

human,mouse,rat

免疫原:

corresponding to a sequence mapping at the 2-215aa of P61106

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Signal Transduction

规格 & 价格:

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Human RAB14 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Immunohistochemistry of Human thyroid cancer using RAB14 Polyclonal Antibody at dilution of 1:30.

通用注释

亚单元:

Interacts with KIF16B (By similarity). Interacts with ZFYVE20.

功能:

Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.

亚细胞位置:

Recycling endosome Early endosome membrane Lipid-anchor Cytoplasmic side Golgi apparatus membrane Lipid-anchor Cytoplasmic side Golgi apparatus Trans-Golgi network membrane Lipid-anchor Cytoplasmic side Cytoplasmic vesicle Phagosome Recruited to recycling endosomes by DENND6A (PubMed:22595670). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).

数据库链接

UniGene:

Hs.371563

SMR:

P61106

STRING:

9606.ENSP00000362946

KEGG:

hsa:51552

MIM:

612673

Pfam: