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S100A1 (基因名), Protein S100-A1 (蛋白名), s10a1_human.

产品名称:

S100A1 Antibody

货号:

P14940Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

S-100 protein alpha chain, S-100 protein subunit alpha, S100 calcium-binding protein A1, S100A

序列号:

P23297

反应性:

human

免疫原:

corresponding to a sequence mapping at the 1-94aa of P23297

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Signal Transduction

规格 & 价格:

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Human S100A1 Polyclonal Antibody

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产品说明书

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R&D 技术数据

Formalin-fixed, paraffin-embedded human melanoma stained with S100A1 antibody using peroxidase-conjugate and AEC chromogen. Note intense cytoplasmic staining of tumor cells.

通用注释

亚单元:

Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain (PubMed:21296671). Also forms heterodimers with S100P (PubMed:15171681). Interacts with AGER (By similarity). Interacts with CAPZA1 (By similarity). Interacts with FKBP4 (PubMed:20188096). Interacts with RYR1 and RYR2 (PubMed:18650434). Interacts with CACYBP in a calcium-dependent manner (PubMed:12042313). Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity (PubMed:22399290).

功能:

Probably acts as a Ca(2+) signal transducer (PubMed:22399290). In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers a conformational change (PubMed:23351007). This conformational change allows interaction of S1001A with specific target proteins, such as TPR-containing proteins, and the modulation of their activity (PubMed:22399290).

亚细胞位置:

Cytoplasm

数据库链接

UniGene:

Hs.515715

SMR:

P23297

STRING:

9606.ENSP00000292169

KEGG:

hsa:6271

MIM: