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SESN3 (基因名), Sestrin-3 (蛋白名), sesn3_human.
产品名称:

SESN3 Antibody

货号:

P0299Rb

商标:
EIAab®
监管等级:
别名:

SEST3

序列号:
P58005
反应性:
human,mouse,rat
免疫原:
corresponding to a sequence mapping at the 310-492aa of P58005
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
-
Human SESN3 Polyclonal Antibody
规格 & 价格: cart
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Human SESN3 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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通用注释


亚单元:
Interacts with the GATOR2 complex which is composed of MIOS, SEC13, SEH1L, WDR24 and WDR59; the interaction is not regulated by leucine (PubMed:25263562, PubMed:26449471). Interacts with RRAGA, RRAGB, RRAGC and RRAGD; may function as a guanine nucleotide dissociation inhibitor for RRAGs and regulate them (PubMed:25259925). Interacts with the TORC2 complex; through RICTOR.


功能:
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity). This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses.


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。
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