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SINHCAF (基因名), SIN3-HDAC complex-associated factor (蛋白名), shcaf_human.

产品名称:

SINHCAF Antibody

货号:

P15272Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Protein FAM60A, Tera protein homolog, L4, C12orf14, FAM60A

序列号:

Q9NP50

反应性:

human

免疫原:

Recombinant human SINHCAF protein ( R15272h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human SINHCAF Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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通用注释

亚单元:

Interacts with the Sin3/HDAC corepressor complex at least composed of BRMS1, BRMS1L, ING2, SAP30, SAP30L and HDAC1 (PubMed:22865885, PubMed:22984288). Found in a complex composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1. Interacts with SIN3A and OGT (By similarity).

功能:

Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway (PubMed:22865885, PubMed:22984288). Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is essential for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming (By similarity).

亚细胞位置:

Nucleus

数据库链接

UniGene:

Hs.505154

STRING:

9606.ENSP00000337477

KEGG:

hsa:58516

MIM:

615027

Pfam: