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SRSF3 (基因名), Serine/arginine-rich splicing factor 3 (蛋白名), srsf3_human.

产品名称:

SRSF3 Antibody

货号:

P11551Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Pre-mRNA-splicing factor SRP20, Splicing factor, arginine/serine-rich 3, SFRS3, SRP20

序列号:

P84103

反应性:

human

免疫原:

corresponding to a sequence mapping at the 1-90aa of P84103

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

Epigenetics

规格 & 价格:

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Human SRSF3 Polyclonal Antibody

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产品说明书

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MSDS:

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R&D 技术数据

Anti-SRSF3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.

通用注释

亚单元:

Interacts with CPSF6 (PubMed:15169763). Interacts with RBMY1A1 (PubMed:15595951). Interacts with SREK1/SFRS12 (PubMed:10757789). Interacts with NXF1 (PubMed:12667464, PubMed:17036044). Interacts with YTHDC1, leading to recruitment to RNA elements adjacent to m6A sites (PubMed:26876937).

功能:

Splicing factor that specifically promotes exon-inclusion during alternative splicing (PubMed:26876937). Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing (PubMed:26876937). Also functions as export adapter involved in mRNA nuclear export such as of histone H2A (PubMed:11336712, PubMed:18364396). Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity (PubMed:11336712, PubMed:18364396). RNA-binding is semi-sequence specific (PubMed:17036044).

亚细胞位置:

Nucleus Nucleus speckle Cytoplasm Recruited to nuclear speckles following interaction with YTHDC1.

数据库链接

UniGene:

Hs.405144

SMR:

P84103

STRING:

9606.ENSP00000362820

KEGG:

hsa:6428

MIM: