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TIRAP (基因名), Toll/interleukin-1 receptor domain-containing adapter protein (蛋白名), tirap_human.
产品名称:

TIRAP Antibody

货号:

P4819Rb-h

商标:
EIAab®
监管等级:
别名:

Adaptor protein Wyatt, MyD88 adapter-like protein, MyD88-2, TIR domain-containing adapter protein, MAL

序列号:
P58753
反应性:
human
免疫原:
Recombinant human TIRAP protein ( R4819h )
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Immunology
Human TIRAP Polyclonal Antibody
规格 & 价格: cart
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Human TIRAP Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
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R&D 技术数据
通用注释


亚单元:
Homodimer. Also forms heterodimers with MYD88. May interact with PIK3AP1 (By similarity). Interacts with TLR4 and IRAK2 via their respective TIR domains. Interacts with BMX and TBK1. Interacts with EIF2AK2. Does not interact with IRAK1, nor TLR9.


功能:
Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.


亚细胞位置:
Cytoplasm Cell membrane Membrane Colocalizes with DAB2IP at the plasma membrane.


该产品尚未在任何出版物中被引用。
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