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TTN (基因名), Titin (蛋白名), titin_human.
产品名称:

TTN Antibody

货号:

P1667Rb-h

商标:
EIAab®
监管等级:
别名:

Connectin, Rhabdomyosarcoma antigen MU-RMS-40.14

序列号:
Q8WZ42
反应性:
human
免疫原:
corresponding to a sequence mapping at the 1-110aa of Q8WZ42
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Signal Transduction
Human TTN Polyclonal Antibody
规格 & 价格: cart
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Human TTN Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemistry-Paraffin: Titin Antibody Analysis of polyclonal antibody to TTN on formalinfixed paraffin-embedded human skeletal muscle Antibody concentration 1.5 ug/mI.
通用注释


亚单元:
Interacts with MYOM1, MYOM2, tropomyosin and myosin. Interacts with actin, primarily via the PEVK domains and with MYPN (By similarity). Interacts with FHL2, NEB, CRYAB, LMNA/lamin-A and LMNB/lamin-B. Interacts with TCAP/telethonin and/or ANK1 isoform Mu17/ank1.5, via the first two N-terminal immunoglobulin domains. Interacts with TRIM63 and TRIM55, through several domains including immunoglobulin domains 141 and 142. Interacts with ANKRD1, ANKRD2 and ANKRD23, via the region between immunoglobulin domains 77 and 78 and interacts with CAPN3, via immunoglobulin domain 79. Interacts with NBR1 through the protein kinase domain. Interacts with CALM/calmodulin. Isoform 6 interacts with OBSCN isoform 3. Interacts with CMYA5.


功能:
Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.


亚细胞位置:
Cytoplasm Nucleus


该产品尚未在任何出版物中被引用。
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