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TLN1 (基因名), Talin-1 (蛋白名), tln1_human.
产品名称:

TLN1 Antibody

货号:

P2104Rb-h

商标:
EIAab®
监管等级:
别名:

KIAA1027, TLN

序列号:
Q9Y490
反应性:
human
免疫原:
corresponding to a sequence mapping at the 2293-2533aa of Q9Y490
形态:
Liquid
存储说明:
4℃ for frequent use, -20℃ to -70℃ for 6 months
缓冲液:
0.1M×PBS,50% glycerol,pH7.5
浓度:
200ug/ml
纯化方式:
Immunogen affinity purified
克隆性:
Polyclonal
亚型:
Rabbit IgG
应用:
推荐产品:
研究领域:
Cancer
Human TLN1 Polyclonal Antibody
规格 & 价格: cart
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Human TLN1 Polyclonal Antibody
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Immunohistochemical of paraffin-embedded human colon cancer using TLN1 antibody at dilution of 1:150.
通用注释


亚单元:
Binds with high affinity to VCL and with low affinity to integrins. Interacts with APBB1IP; this inhibits VCL binding. Interacts with PTK2/FAK1 (By similarity). Interacts with PIP5K1C and NRAP. Interacts with LAYN. Interacts with SYNM. Interacts with ITGB1; the interaction is prevented by competitive binding of ITGB1BP1. Interacts with human cytomegalovirus protein UL135.


功能:
Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.


亚细胞位置:
Cell projection Ruffle membrane Peripheral membrane protein Cytoplasmic side Cytoplasm Cytoskeleton Cell surface Cell junction Focal adhesion Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity).


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