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TRRAP (基因名), Transformation/transcription domain-associated protein (蛋白名), trrap_human.

产品名称:

TRRAP Antibody

货号:

P13003Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

350/400 kDa PCAF-associated factor, STAF40, Tra1 homolog, PAF350/400, PAF400

序列号:

Q9Y4A5

反应性:

human

免疫原:

Recombinant human TRRAP protein ( R13003h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

关注

Human TRRAP Polyclonal Antibody

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产品说明书

数据表:

MSDS:

在线询价

数据
文献
序列 / 3D
常见问题解答
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R&D 技术数据

Immunohistochemical staining of human liver with TRRAP polyclonal antibody at 1:200 dilution.

通用注释

亚单元:

Interacts with MYC, E2F1 and E2F4 transcription factors. Interacts directly with p53/TP53. Interacts with GCN5L2. Component of various HAT complexes. Component of the PCAF complex, at least composed of TADA2L/ADA2, SUPT3H, TADA3L/ADA3, TAF5L/PAF65-beta, TAF6L/PAF65-alpha, TAF10/TAFII30, TAF12/TAFII20, TAF9/TAFII31 and TRRAP. Component of the TFTC-HAT complex, at least composed of TAF5L, TAF6L, TADA3L, SUPT3H/SPT3, TAF2/TAFII150, TAF4/TAFII135, TAF5/TAFII100, GCN5L2/GCN5, TAF10 and TRRAP. Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6. Component of the STAGA complex, at least composed of SUPT3H, GCN5L2, SUPT7L, TAF5L, TAF6L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9. The STAGA core complex is associated with a subcomplex required for histone deubiquitination composed of ATXN7L3, ENY2 and USP22. Component of the BAF53 complex, at least composed of BAF53A, RUVBL1, SMARCA4/BRG1, and TRRAP, which preferentially acetylates histone H4 (and H2A) within nucleosomes. Interacts with NPAT. Interaction with TELO2 AND TTI1. Component of a SWR1-like complex.

功能:

Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Component of the NuA4 histone acetyltransferase complex which is responsible for acetylation of nucleosomal histones H4 and H2A. Plays a central role in MYC transcription activation, and also participates in cell transformation by MYC. Required for p53/TP53-, E2F1- and E2F4-mediated transcription activation. Also involved in transcription activation mediated by the adenovirus E1A, a viral oncoprotein that deregulates transcription of key genes. Probably acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation. Probably not required in the steps following histone acetylation in processes of transcription activation. May be required for the mitotic checkpoint and normal cell cycle progression. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.

亚细胞位置:

Nucleus

数据库链接

UniGene:

Hs.203952

STRING:

9606.ENSP00000347733

KEGG:

hsa:8295

MIM:

603015

Pfam:

PF02259

Uniprot:

Q9Y4A5

相关产品

Mouse Trrap ELISA Kit

Mouse Trrap CLIA Kit

Mouse Trrap Protein

Mouse Trrap Polyclonal Antibody

Mouse Trrap Monoclonal Antibody

序列长度:

3859

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MDPAWHPWL

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该产品尚未在任何出版物中被引用。

[1].

多克隆抗体TRRAP可以申请产品的免费试用装吗？

我们不提供作测试目的的免费样品或试用装样品。如果某种抗体的性能与说明书上的数据说明不同，我们将提供换货或退款服务。如果抗体用于未测试的物种或应用，我们不提供换货或退款服务。EIAab产品的投诉期为6个月，逾期不予受理。

[2].

多克隆抗体TRRAP说明书上的信息是及时更新的吗？

说明书包含了我们能获得的关于该产品的最新信息。当我们获得另外的信息时，说明书会实时更新，因此说明书绝不会过时。

[3].

如何选择合适的一抗？

请先确定您要检测的种属和使用的实验方法，然后查找相关产品，根据说明书上描述的“种属和应用”来确定合适的抗体。如果说明书中有明确您要检测的种属和实验方法均经过检测，则您可以放心地购买该产品。

[4].

多克隆抗体TRRAP在其他物种或应用中测试过吗？

所有我们测试过抗体的物种和应用都会在说明书上说明。我们获取新信息后，就会立即更新物种和应用。

[5].

如何保存多克隆抗体TRRAP？

我们建议始终按照说明书上的方法保存抗体。如果没有按照说明书上的说明保存，我们不能保证抗体的性能。

[6].

如何分装多克隆抗体TRRAP？

请根据一次实验的常用量进行分装。每等份不应少于10μl；每等份的量越少，抗体储液浓度受蒸发和管壁吸附的影响越大。

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