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TYROBP (基因名), TYRO protein tyrosine kinase-binding protein (蛋白名), tyobp_human.

产品名称:

TYROBP Antibody

货号:

P12665Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

DNAX-activation protein 12, Killer-activating receptor-associated protein, KAR-associated protein, DAP12, KARAP

序列号:

O43914

反应性:

human

免疫原:

corresponding to a sequence mapping at the 22-113aa of O43914

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human TYROBP Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Immunohistochemical staining of paraffin embedded human lung carcinoma tissue using TYROBP antibody dilution at: 1:50.

通用注释

亚单元:

Homodimer; disulfide-linked. Interacts with SIRPB1 and TREM1. Interacts with CLECSF5. Interacts with SIGLEC14. Interacts with CD300LB and CD300E. Interacts with CD300D (By similarity). Interacts (via ITAM domain) with SYK (via SH2 domains); activates SYK mediating neutrophils and macrophages integrin-mediated activation (By similarity). Interacts with KLRC2 and KIR2DS3.

功能:

Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin.

亚细胞位置:

Membrane Single-pass type I membrane protein

数据库链接

UniGene:

Hs.515369

SMR:

O43914

STRING:

9606.ENSP00000262629

KEGG:

hsa:7305

MIM: