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SLC14A1 (基因名), Urea transporter 1 (蛋白名), ut1_human.

产品名称:

SLC14A1 Antibody

货号:

P12521Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Solute carrier family 14 member 1, Urea transporter, erythrocyte, HUT11, JK, RACH1, UT1, UTE

序列号:

Q13336

反应性:

human

免疫原:

corresponding to a sequence mapping at the 1-240aa of Q13336

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human SLC14A1 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

ImmunohistochemistrY analysis of human kidney tissue using an anti-SLCI4A1 polyclonal antibody.

通用注释

亚单元:

Homotrimer; each subunit contains a pore through which urea permeates. Identified in a complex with STOM.

功能:

Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means.

亚细胞位置:

Cell membrane Multi-pass membrane protein Basolateral cell membrane Multi-pass membrane protein Restricted to the basolateral membrane in various portions of the urothelium.

数据库链接

UniGene:

Hs.101307

SMR:

Q13336

STRING:

9606.ENSP00000390637

KEGG:

hsa:6563

MIM:

111000

Pfam: