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WRAP73 (基因名), WD repeat-containing protein WRAP73 (蛋白名), wrp73_human.

产品名称:

WRAP73 Antibody

货号:

P2977Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

WD repeat-containing protein 8, WD repeat-containing protein antisense to TP73 gene, WDR8

序列号:

Q9P2S5

反应性:

human

免疫原:

Recombinant human WRAP73 protein ( R2977h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human WRAP73 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

lmmunohistochemistry:WRAP73 antibody Staining of human esophagus shows strong nuclear positivity in squamous epithelial cells.

通用注释

亚单元:

Interacts with SSX2IP.

功能:

The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology (PubMed:26545777). Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal body during ciliogenesis; may promote docking of RAB8A- and ARL13B-containing vesicles (PubMed:26675238).

亚细胞位置:

Cytoplasm Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Centriole Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Centriolar satellite Enriched in the proximal end of the mother centriole (PubMed:26545777). During ciliogenesis also associated with the basal body of the adjacent centriole (PubMed:26675238).

数据库链接

UniGene:

Hs.31714

STRING:

9606.ENSP00000270708

KEGG:

hsa:49856

MIM:

606040

Pfam:

PF12894

Uniprot: