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FCGR3A (基因名), Low affinity immunoglobulin gamma Fc region receptor III-A (蛋白名), 10743_eiaab.
产品名称:

Human FCGR3A/ Low affinity immunoglobulin gamma Fc region receptor III-A Recombinant Protein
低亲和力免疫球蛋白Fc区Ⅲ受体γ

货号:

R1580-1h

商标:
EIAab®
监管等级:
别名:

CD16a antigen, Fc-gamma RIII-alpha, FcR-10, IgG Fc receptor III-2, Fc-gamma RIII, CD16a, CD16A, FCG3, FCGR3, IGFR3

序列号:
P08637
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human FCGR3A Protein
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Human FCGR3A Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1q23.3 by HGNC 1q23.3 by Entrez Gene 1q23.3 by Ensembl
FCGR3A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Exists as a heterooligomeric receptor complex with Fc epsilon receptor I gamma subunit and / or the CD3 zeta subunit. Interacts with INPP5D/SHIP1.


功能:
Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.


亚细胞位置:
Cell membrane Single-pass type I membrane protein Secreted Exists also as a soluble receptor.


该产品尚未在任何出版物中被引用。

[1].
"Analysis of MIF, FCGR2A and FCGR3A gene polymorphisms with susceptibility to pulmonary tuberculosis in Moroccan population."

[2].
"Copy number variation of FCGR3A rather than FCGR3B and FCGR2B is associated with susceptibility to anti-GBM disease."

[3].
"Fcgamma receptor IIIA polymorphisms and efficacy of rituximab therapy on Chinese diffuse large B-cell lymphoma."

[4].
"[Association of Fc gamma receptors IIIA gene polymorphisms with the susceptibility to periodontitis in Chinese patients]."

[5].
"Contribution of Fcgamma receptor IIIA gene 158V/F polymorphism and copy number variation to the risk of ACPA-positive rheumatoid arthritis."

[6].
"Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer."

[7].
"Associations between FCGR3A polymorphisms and susceptibility to rheumatoid arthritis: a metaanalysis."

[8].
"Genetic susceptibility and haplotype analysis between Fcgamma receptor IIB and IIIA gene with systemic lupus erythematosus in Chinese population."

[9].
"Genetic linkage of Fc gamma RIIa and Fc gamma RIIIa and implications for their use in predicting clinical responses to CD20-directed monoclonal antibody therapy."

[10].
"Association between SLE nephritis and polymorphic variants of the CRP and FcgammaRIIIa genes."
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