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首页  >  重组蛋白  >  Rat C3 Recombinant Protein
C3 (基因名), Complement C3 (蛋白名), co3_rat.
产品名称:

Rat C3/ Complement C3 Recombinant Protein
补体蛋白3

货号:

R0861r

商标:
EIAab®
监管等级:
序列号:
P01026
来源:
E.coli
种属:
Rat
标签:
His
序列:
1431-1663aa
预估分子量:
25.63 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Rat C3 Protein
规格 & 价格: cart
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Rat C3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
Rat C3 Protein
Recombinant rat C3 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
通用注释


亚单元:
C3 precursor is first processed by the removal of 4 Arg residues, forming two chains, beta and alpha, linked by a disulfide bond. C3 convertase activates C3 by cleaving the alpha chain, releasing C3a anaphylatoxin and generating C3b (beta chain + alpha' chain). C3dg interacts with CR2 (via the N-terminal Sushi domains 1 and 2). Interacts with VSIG4. Interacts (both C3a and ASP) with C5AR2; the interaction occurs with higher affinity for ASP, enhancing the phosphorylation and activation of C5AR2, recruitment of ARRB2 to the cell surface and endocytosis of GRP77.


功能:
Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。
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