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GAD2 (基因名), Glutamate decarboxylase 2 (蛋白名), dce2_human.
产品名称:

Human GAD2/ Glutamate decarboxylase 2 Recombinant Protein
谷氨酸脱羧酶2

货号:

R0157h

商标:
EIAab®
监管等级:
别名:

65 kDa glutamic acid decarboxylase, Glutamate decarboxylase 65 kDa isoform, GAD-65, GAD65

序列号:
Q05329
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cell Biology
Human GAD2 Protein
规格 & 价格: cart
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Human GAD2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 10p12.1 by HGNC 10p12.1 by Entrez Gene 10p12.1 by Ensembl
GAD2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer.


功能:
Catalyzes the production of GABA.


亚细胞位置:
Cytoplasm Cytosol Cytoplasmic vesicle Cell junction Synapse Presynaptic cell membrane Lipid-anchor Golgi apparatus membrane Peripheral membrane protein Cytoplasmic side Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.


该产品尚未在任何出版物中被引用。

[1].
"Association analysis of the glutamic acid decarboxylase 2 and the glutamine synthetase genes (GAD2, GLUL) with schizophrenia."

[2].
"GAD2 gene sequence variations are associated with eating behaviors and weight gain in women from the Quebec family study."

[3].
"GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop."

[4].
"A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects."

[5].
"Mutation screen of the GAD2 gene and association study of alcoholism in three populations."

[6].
"Lack of support for the association between GAD2 polymorphisms and severe human obesity."

[7].
"Is glutamate decarboxylase 2 (GAD2) a genetic link between low birth weight and subsequent development of obesity in children?"

[8].
"GAD2 on chromosome 10p12 is a candidate gene for human obesity."

[9].
"A comprehensive, statistically powered analysis of GAD2 in type 1 diabetes."

[10].
"A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65."
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