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ODC1 (基因名), Ornithine decarboxylase (蛋白名), dcor_human.
产品名称:

Human ODC1/ Ornithine decarboxylase Recombinant Protein
鸟氨酸脱羟

货号:

R1332h

商标:
EIAab®
监管等级:
别名:

ODC

序列号:
P11926
来源:
E.coli
种属:
Human
标签:
His
序列:
CLQKRPKPDEKYYSSSIW
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cell Biology
Human ODC1 Protein
规格 & 价格: cart
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Human ODC1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 2p25.1 by HGNC 2p25.1 by Entrez Gene 2p25.1 by Ensembl
ODC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer. Only the dimer is catalytically active, as the active sites are constructed of residues from both monomers (Probable). Does not form a heterodimer with AZIN2.


功能:
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"Genetic polymorphism in ornithine decarboxylase and risk of breast cancer."

[2].
"Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase."

[3].
"Ornithine decarboxylase polymorphism modification of response to aspirin treatment for colorectal adenoma prevention."

[4].
"Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene."

[5].
"Nitric oxide inhibits ornithine decarboxylase via S-nitrosylation of cysteine 360 in the active site of the enzyme."

[6].
"Crystal structure of human ornithine decarboxylase at 2.1 A resolution: structural insights to antizyme binding."

[7].
"Regulation of ornithine decarboxylase mRNA levels in human breast cancer cells: pattern of expression and involvement of core enhancer promoter element."

[8].
"Expression of human chromosome 2 ornithine decarboxylase gene in ornithine decarboxylase-deficient Chinese hamster ovary cells."

[9].
"Structural basis of antizyme-mediated regulation of polyamine homeostasis."

[10].
"The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification."
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