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DEFB1 (基因名), Beta-defensin 1 (蛋白名), defb1_human.
产品名称:

Human DEFB1/ Beta-defensin 1 Recombinant Protein
β防御素1

货号:

R0352h

商标:
EIAab®
监管等级:
别名:

Defensin, beta 1, BD-1, BD1, HBD1

序列号:
P60022
来源:
E.coli
种属:
Human
标签:
His
序列:
33-68aa
预估分子量:
3.96 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human DEFB1 Protein
规格 & 价格: cart
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Human DEFB1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 8p23.1 by HGNC 8p23.1 by Entrez Gene 8p23.1 by Ensembl
DEFB1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636).


亚细胞位置:
Secreted



[1].
"hBD-1: a novel beta-defensin from human plasma."

[2].
"Association between DEFB1 gene haplotype and herpes viruses seroprevalence in children with acute lymphoblastic leukemia."

[3].
"SNP 668C (-44) alters a NF-kappaB1 putative binding site in non-coding strand of human beta-defensin 1 (DEFB1) and is associated with lepromatous leprosy."

[4].
"Potential role of human beta-defensin 1 in Helicobacter pylori-induced gastritis."

[5].
"Distribution of human beta-defensin polymorphisms in various control and cystic fibrosis populations."

[6].
"Association of defensin beta-1 gene polymorphisms with asthma."

[7].
"Single-nucleotide polymorphisms (SNPs) in human beta-defensin 1: high-throughput SNP assays and association with Candida carriage in type I diabetics and nondiabetic controls."

[8].
"Genetic variants of human beta-defensin-1 and chronic obstructive pulmonary disease."

[9].
"The structure of human beta-defensin-1: new insights into structural properties of beta-defensins."

[10].
"Human airway epithelia express a beta-defensin."
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