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ECM1 (基因名), Extracellular matrix protein 1 (蛋白名), ecm1_human.
产品名称:

Human ECM1/ Extracellular matrix protein 1 Recombinant Protein
细胞外基质蛋白1

货号:

R1864h

商标:
EIAab®
监管等级:
别名:

Secretory component p85

序列号:
Q16610
来源:
E.coli
种属:
Human
标签:
His
序列:
33-172aa
预估分子量:
15.4 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
  • Human ECM1 Protein
  • Human ECM1 Protein
  • Human ECM1 Protein
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Human ECM1 Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human ECM1 Protein
The PCR product of human ECM1 gene was determined by 1% Agarose stained with EB.
Human ECM1 Protein
Recombinant human ECM1 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 1q21.2 by HGNC 1q21.2 by Entrez Gene 1q21.2 by Ensembl
ECM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts (via C-terminus) with HSPG2 (via C-terminus). Interacts with EFEMP1/FBLN3 and LAMB3. Interacts with MMP9.


功能:
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.


亚细胞位置:
Secreted Extracellular space Extracellular matrix


该产品尚未在任何出版物中被引用。

[1].
"The human extracellular matrix gene 1 (ECM1): genomic structure, cDNA cloning, expression pattern, and chromosomal localization."

[2].
"Characterization of the human extracellular matrix protein 1 gene on chromosome 1q21."

[3].
"Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk."

[4].
"ECM1 interacts with fibulin-3 and the beta 3 chain of laminin 332 through its serum albumin subdomain-like 2 domain."

[5].
"Extracellular matrix protein 1 inhibits the activity of matrix metalloproteinase 9 through high-affinity protein/protein interactions."

[6].
"Extracellular matrix protein 1 gene (ECM1) mutations in lipoid proteinosis and genotype-phenotype correlation."

[7].
"Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis."

[8].
"Lipoid proteinosis maps to 1q21 and is caused by mutations in the extracellular matrix protein 1 gene (ECM1)."

[9].
"Recombinant human extracellular matrix protein 1 inhibits alkaline phosphatase activity and mineralization of mouse embryonic metatarsals in vitro."

[10].
"Extracellular matrix protein 1 (ECM1) has angiogenic properties and is expressed by breast tumor cells."
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