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EDAR (基因名), Tumor necrosis factor receptor superfamily member EDAR (蛋白名), edar_human.
产品名称:

Human EDAR/ Tumor necrosis factor receptor superfamily member EDAR Recombinant Protein
肿瘤坏死因子受体超家族成员EDAR

货号:

R15171h

商标:
EIAab®
监管等级:
别名:

Anhidrotic ectodysplasin receptor 1, Downless homolog, EDA-A1 receptor, Ectodermal dysplasia receptor, Ectodysplasin-A receptor, DL

序列号:
Q9UNE0
来源:
E.coli
种属:
Human
标签:
His
序列:
209-448aa
预估分子量:
26.4 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human EDAR Protein
规格 & 价格: cart
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Human EDAR Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 2q13 by HGNC 2q13 by Entrez Gene 2q13 by Ensembl
EDAR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Binds to EDARADD. Associates with TRAF1, TRAF2, TRAF3 and NIK.


功能:
Receptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death.


亚细胞位置:
Membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia."

[2].
"Identification of mutations in the EDA and EDAR genes in Pakistani families with hypohidrotic ectodermal dysplasia."

[3].
"A common variation in EDAR is a genetic determinant of shovel-shaped incisors."

[4].
"A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness."

[5].
"Mutation screening of the Ectodysplasin-A receptor gene EDAR in hypohidrotic ectodermal dysplasia."
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