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EEA1 (基因名), Early endosome antigen 1 (蛋白名), eea1_human.
产品名称:

Human EEA1/ Early endosome antigen 1 Recombinant Protein
MouseEarlyendosomeantigen1

货号:

R15168h

商标:
EIAab®
监管等级:
别名:

Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2, ZFYVE2

序列号:
Q15075
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human EEA1 Protein
规格 & 价格: cart
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Human EEA1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 12q22 by HGNC 12q22 by Entrez Gene 12q22 by Ensembl
EEA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding. Interacts with RAB31. Interacts with ERBB2. Interacts with SAMD9 AND SAMD9L (PubMed:24029230). May interact with PLEKHF2.


功能:
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.


亚细胞位置:
Cytoplasm Early endosome membrane Peripheral membrane protein


该产品尚未在任何出版物中被引用。

[1].
"EEA1 links PI(3)K function to Rab5 regulation of endosome fusion."

[2].
"Structural mechanism of endosome docking by the FYVE domain."

[3].
"Direct interaction of EEA1 with Rab5b."

[4].
"The Rab5 effector EEA1 interacts directly with syntaxin-6."

[5].
"EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif."
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