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EFNA4 (基因名), Ephrin-A4 (蛋白名), efna4_human.
产品名称:

Human EFNA4/ Ephrin-A4 Recombinant Protein

货号:

R10771h

商标:
EIAab®
监管等级:
别名:

EPH-related receptor tyrosine kinase ligand 4, LERK-4, EPLG4, LERK4

序列号:
P52798
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human EFNA4 Protein
规格 & 价格: cart
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Human EFNA4 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1q21.3 by HGNC 1q21.3 by Entrez Gene 1q21.3 by Ensembl
EFNA4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.


亚细胞位置:
Isoform 2 Secreted


该产品尚未在任何出版物中被引用。

[1].
"A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes."

[2].
"The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3."

[3].
"Ephrin A4 expression in osteosarcoma, impact on prognosis, and patient outcome."

[4].
"Prevalence and complications of single-gene and chromosomal disorders in craniosynostosis."

[5].
"Expression profile of Eph receptors and ephrin ligands in healthy human B lymphocytes and chronic lymphocytic leukemia B-cells."

[6].
"An impaired transendothelial migration potential of chronic lymphocytic leukemia (CLL) cells can be linked to ephrin-A4 expression."

[7].
"Cell mixing at a neural crest-mesoderm boundary and deficient ephrin-Eph signaling in the pathogenesis of craniosynostosis."

[8].
"The DNA sequence and biological annotation of human chromosome 1."

[9].
"Signal peptide prediction based on analysis of experimentally verified cleavage sites."

[10].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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