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EGFLAM (基因名), Pikachurin (蛋白名), egfla_human.
产品名称:

Human EGFLAM/ Pikachurin Recombinant Protein
Pikachurin

货号:

R2405h

商标:
EIAab®
监管等级:
别名:

Agrin-like protein, EGF-like, fibronectin type-III and laminin G-like domain-containing protein, AGRINL, AGRNL, PIKA

序列号:
Q63HQ2
来源:
E.coli
种属:
Human
标签:
His
序列:
801-1017aa
预估分子量:
23.87 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human EGFLAM Protein
规格 & 价格: cart
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Human EGFLAM Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human EGFLAM Protein
Recombinant human EGFLAM protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 5p13.2-p13.1 by HGNC 5p13.2-p13.1 by Entrez Gene 5p13.2-p13.1 by Ensembl
EGFLAM Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with DAG1 alpha-dystroglycan.


功能:
Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness (By similarity).


亚细胞位置:
Secreted Extracellular space Extracellular matrix Cell junction Synapse Detected in the synaptic cleft of the ribbon synapse around the postsynaptic terminals of bipolar cells. Colocalizes with BSN, CTBP2 and DAG1 in photoreceptor synaptic terminals.



[1].
"Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D."

[2].
"[Model of aberrant DNA methylation patterns and its applications in epithelial ovarian cancer.]."

[3].
"Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation."

[4].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[5].
"Identification of EGFLAM, SPATC1L and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies."
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