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PFKFB4 (基因名), 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (蛋白名), f264_human.
产品名称:

Human PFKFB4/ 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 Recombinant Protein
6-磷酸果糖2-激酶/果糖-2,6-双磷酸酶4

货号:

R10217h

商标:
EIAab®
监管等级:
别名:

6PF-2-K/Fru-2, 6-P2ase testis-type isozyme, 6PF-2-K/Fru-2, 6-P2ase 4

序列号:
Q16877
来源:
E.coli
种属:
Human
标签:
His
序列:
258-367aa
预估分子量:
12.1 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
  • Human PFKFB4 Protein
  • Human PFKFB4 Protein
  • Human PFKFB4 Protein
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Human PFKFB4 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human PFKFB4 Protein
The PCR product of human PFKFB4 gene was determined by 1% Agarose stained with EB.
Human PFKFB4 Protein
Recombinant human PFKFB4 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 3p21.31 by HGNC 3p21.31 by Entrez Gene 3p21.31 by Ensembl
PFKFB4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer.


功能:
Synthesis and degradation of fructose 2,6-bisphosphate.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"Cloning, expression and chromosomal localization of a human testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene."

[2].
"Specific expression of pfkfb4 gene in spermatogonia germ cells and analysis of its 5'-flanking region."

[3].
"Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation."

[4].
"Cloning of cDNA encoding for a novel isozyme of fructose 6-phosphate, 2-kinase/fructose 2,6-bisphosphatase from human placenta."

[5].
"Fructose-2,6-bisphosphate synthesis by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth."

[6].
"Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers."

[7].
"Overexpression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4 in the human breast and colon malignant tumors."

[8].
"Splice isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-4: expression and hypoxic regulation."

[9].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[10].
"Analysis of Malignant Melanoma Cell Lines Exposed to Hypoxia Reveals the Importance of PFKFB4 Overexpression for Disease Progression."
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