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F10 (基因名), Coagulation factor X (蛋白名), fa10_human.
产品名称:

Human F10/ Coagulation factor X Recombinant Protein
凝血因子X

货号:

R0834h

商标:
EIAab®
监管等级:
别名:

Stuart factor, Stuart-Prower factor

序列号:
P00742
来源:
E.coli
种属:
Human
标签:
His
序列:
41-488aa
预估分子量:
49.28 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human F10 Protein
规格 & 价格: cart
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Human F10 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human F10 Protein
Recombinant human F10 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 13q34 by HGNC 13q34 by Entrez Gene 13q34 by Ensembl
F10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds. Forms a heterodimer with SERPINA5.


功能:
Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Characterization of a homozygous Gly11Val mutation in the Gla domain of coagulation factor X."

[2].
"Impaired prothrombinase activity of factor X Gly381Asp results in severe familial CRM+ FX deficiency."

[3].
"Structure of human des(1-45) factor Xa at 2.2 A resolution."

[4].
"Cloning and expression in COS-1 cells of a full-length cDNA encoding human coagulation factor X."

[5].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[6].
"Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals."

[7].
"Association of genetic variants with hemorrhagic stroke in Japanese individuals."

[8].
"Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth."

[9].
"Recent estimates of the structure of the factor VIIa (FVIIa)/tissue factor (TF) and factor Xa (FXa) ternary complex."

[10].
"Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa."
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