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F11 (基因名), Coagulation factor XI (蛋白名), fa11_human.
产品名称:

Human F11/ Coagulation factor XI Recombinant Protein
凝血因子XI

货号:

R0850h

商标:
EIAab®
监管等级:
别名:

Plasma thromboplastin antecedent, PTA, FXI

序列号:
P03951
来源:
E.coli
种属:
Human
标签:
His
序列:
388-625aa
预估分子量:
26.18 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human F11 Protein
规格 & 价格: cart
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Human F11 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 4q35.2 by HGNC 4q35.2 by Entrez Gene 4q35.2 by Ensembl
F11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer; disulfide-linked. Forms a heterodimer with SERPINA5. After activation the heavy and light chains are also linked by a disulfide bond.


功能:
Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Seven novel point mutations in the F11 gene in Iranian FXI-deficient patients."

[2].
"Factor XI deficiency in French Basques is caused predominantly by an ancestral Cys38Arg mutation in the factor XI gene."

[3].
"Identification of a novel mutation in a non-Jewish factor XI deficient kindred."

[4].
"Heterozygous factor XI deficiency associated with three novel mutations."

[5].
"Expression of human blood coagulation factor XI: characterization of the defect in factor XI type III deficiency."

[6].
"Site-specific N-glycosylation analysis of human factor XI: Identification of a noncanonical NXC glycosite."

[7].
"Population-specific spectrum of the F11 mutations in Koreans: evidence for a founder effect."

[8].
"A cluster of factor XI-deficient patients due to a new mutation (Ile 436 Lys) in northeastern Italy."

[9].
"Revisiting the molecular epidemiology of factor XI deficiency: nine new mutations and an original large 4qTer deletion in western Brittany (France)."

[10].
"Identification of a novel F11 missense mutation (Ile463Ser) in a family with congenital factor XI deficiency."
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