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F7 (基因名), Coagulation factor VII (蛋白名), fa7_human.
产品名称:

Human F7/ Coagulation factor VII Recombinant Protein
凝血因子Ⅶ

货号:

R1874h

商标:
EIAab®
监管等级:
别名:

Proconvertin, Serum prothrombin conversion accelerator, SPCA

序列号:
P08709
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Human F7 Protein
规格 & 价格: cart
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Human F7 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 13q34 by HGNC 13q34 by Entrez Gene 13q34 by Ensembl
F7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Heterodimer of a light chain and a heavy chain linked by a disulfide bond.


功能:
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study."

[2].
"Factor VII deficiency: clinical manifestation of 717 subjects from Europe and Latin America with mutations in the factor 7 gene."

[3].
"[The connection between Arg353Gln polymorphism of coagulation factor VII and recurrent miscarriages]."

[4].
"Coagulation factor VII and inflammatory markers in patients with coronary heart disease."

[5].
"Coagulation factor VII gene haplotypes, obesity-related traits, and cardiovascular risk in young women."

[6].
"Tissue factor and coagulation factor VII levels during acute myocardial infarction: association with genotype and adverse events."

[7].
"Common genetic variation in five thrombosis genes and relations to plasma hemostatic protein level and cardiovascular disease risk."

[8].
"Human F7 sequence is split into three deep clades that are related to FVII plasma levels."

[9].
"The F7 gene and clotting factor VII levels: dissection of a human quantitative trait locus."

[10].
"The effects of long-term diet and omega-3 fatty acid supplementation on coagulation factor VII and serum phospholipids with special emphasis on the R353Q polymorphism of the FVII gene."
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