EIAab
首页  >  重组蛋白  >  Human FAF2 Recombinant Protein
FAF2 (基因名), FAS-associated factor 2 (蛋白名), faf2_human.
产品名称:

Human FAF2/ FAS-associated factor 2 Recombinant Protein
FAS相关因子2

货号:

R6959h

商标:
EIAab®
监管等级:
别名:

Protein ETEA, UBX domain-containing protein 3B, UBX domain-containing protein 8, ETEA, KIAA0887, UBXD8, UBXN3B

序列号:
Q96CS3
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human FAF2 Protein
规格 & 价格: cart
×
Human FAF2 Protein
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 5q35.2 by HGNC 5q35.2 by Entrez Gene 5q35.2 by Ensembl
FAF2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Identified in a complex that contains SEL1L, OS9, FAF2/UBXD8, UBE2J1/UBC6E and AUP1 (PubMed:18711132). Interacts with YOD1 (PubMed:19818707). Interacts (via N-terminus) with UBQLN2 (via C-terminus) (PubMed:24215460). Interacts with PNPLA2 and UBAC2 (PubMed:23297223).


功能:
Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis (PubMed:23297223).


亚细胞位置:
Cytoplasm Lipid droplet Endoplasmic reticulum


该产品尚未在任何出版物中被引用。

[1].
"Cloning and characterization of the highly expressed ETEA gene from blood cells of atopic dermatitis patients."

[2].
"Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."

[3].
"Signal-peptide-mediated translocation is regulated by a p97-AIRAPL complex."

[4].
"Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation."

[5].
"Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com