EIAab
首页  >  重组蛋白  >  Human FCMR Recombinant Protein
FCMR (基因名), Fas apoptotic inhibitory molecule 3 (蛋白名), faim3_human.
产品名称:

Human FCMR/ Fas apoptotic inhibitory molecule 3 Recombinant Protein
Fas凋亡抑制分子3

货号:

R15361h

商标:
EIAab®
监管等级:
别名:

IgM Fc fragment receptor, Regulator of Fas-induced apoptosis Toso, FAIM3, TOSO

序列号:
O60667
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human FCMR Protein
规格 & 价格: cart
×
Human FCMR Protein
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1q32.1 by HGNC 1q32.1 by Entrez Gene 1q32.1 by Ensembl
FCMR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.


亚细胞位置:
Isoform 3 Secreted Detected in the serum.


该产品尚未在任何出版物中被引用。

[1].
"Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells."

[2].
"Nomenclature of Toso, Fas apoptosis inhibitory molecule 3, and IgM FcR."

[3].
"Enhanced levels of both the membrane-bound and soluble forms of IgM Fc receptor (FcμR) in patients with chronic lymphocytic leukemia."

[4].
"Effects of misoprostol on the pharmacokinetics of indomethacin in human volunteers."

[5].
"Overexpression of Fc mu receptor (FCMR, TOSO) gene in chronic lymphocytic leukemia patients."

[6].
"Toso, a functional IgM receptor, is regulated by IL-2 in T and NK cells."

[7].
"TOSO is overexpressed and correlated with disease progression in Chinese patients with chronic lymphocytic leukemia."

[8].
"Toso regulates the balance between apoptotic and nonapoptotic death receptor signaling by facilitating RIP1 ubiquitination."

[9].
"[Expression and prognostic significance of TOSO in CD19+ B cells from Chinese CLL patients]."

[10].
"TOSO, the Fcmicro receptor, is highly expressed on chronic lymphocytic leukemia B cells, internalizes upon IgM binding, shuttles to the lysosome, and is downregulated in response to TLR activation."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com