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FCGR2A (基因名), Low affinity immunoglobulin gamma Fc region receptor II-a (蛋白名), fcg2a_human.
产品名称:

Human FCGR2A/ Low affinity immunoglobulin gamma Fc region receptor II-a Recombinant Protein
低亲和力免疫球蛋白?gammaFc区受体2-a

货号:

R1579h

商标:
EIAab®
监管等级:
别名:

CDw32, Fc-gamma RII-a, Fc-gamma-RIIa, CD32, IgG Fc receptor II-a, CD32, FCG2, FCGR2A1, IGFR2

序列号:
P12318
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Human FCGR2A Protein
规格 & 价格: cart
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Human FCGR2A Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1q23.3 by HGNC 1q23.3 by Entrez Gene 1q23.3 by Ensembl
FCGR2A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with INPP5D/SHIP1 and INPPL1/SHIP2, regulating its function. Interacts with APCS and FGR. Interacts with HCK.


功能:
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.


亚细胞位置:
Cell membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。

[1].
"CRP and FCGR2A genes have an epistatic effect on carotid artery intima-media thickness: the Cardiovascular Risk in Young Finns Study."

[2].
"FcgammaRIIa (CD32) polymorphism and anti-malarial IgG subclass pattern among Fulani and sympatric ethnic groups living in eastern Sudan."

[3].
"FcgammaRIIa genotype is associated with acute coronary syndromes as first manifestation of coronary artery disease."

[4].
"FcgammaRIIa, IIIa and IIIb gene polymorphisms in Beh?et's disease: do they have any clinical implications?"

[5].
"FcgammaRIIa polymorphism and clinical response to rituximab in non-Hodgkin lymphoma patients."

[6].
"Fc gamma RIIa (CD32) polymorphism and onchocercal skin disease: implications for the development of severe reactive onchodermatitis (ROD)."

[7].
"FcgammaRIIIA and FcgammaRIIA polymorphisms do not predict clinical outcome of follicular non-Hodgkin's lymphoma patients treated with sequential CHOP and rituximab."

[8].
"The efficacy of rituximab plus Hyper-CVAD regimen in mantle cell lymphoma is independent of FCgammaRIIIa and FCgammaRIIa polymorphisms."

[9].
"Genetic linkage of Fc gamma RIIa and Fc gamma RIIIa and implications for their use in predicting clinical responses to CD20-directed monoclonal antibody therapy."

[10].
"Multiplex family-based study in systemic lupus erythematosus: association between the R620W polymorphism of PTPN22 and the FcgammaRIIa (CD32A) R131 allele."
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