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FCGR3B (基因名), Low affinity immunoglobulin gamma Fc region receptor III-B (蛋白名), fcg3b_human.
产品名称:

Human FCGR3B/ Low affinity immunoglobulin gamma Fc region receptor III-B Recombinant Protein
低亲和免疫球蛋白Fc区B受体γ

货号:

R9986h

商标:
EIAab®
监管等级:
别名:

Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, Fc-gamma RIII, CD16b, CD16B, FCG3, FCGR3, IGFR3

序列号:
O75015
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human FCGR3B Protein
规格 & 价格: cart
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Human FCGR3B Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1q23.3 by HGNC 1q23.3 by Entrez Gene 1q23.3 by Ensembl
FCGR3B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Monomer. Interacts with INPP5D/SHIP1.


功能:
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.


亚细胞位置:
Cell membrane Lipid-anchor GPI-anchor Secreted Secreted after cleavage.


该产品尚未在任何出版物中被引用。

[1].
"Copy number variation of FCGR3A rather than FCGR3B and FCGR2B is associated with susceptibility to anti-GBM disease."

[2].
"Common polymorphisms in critical genes of innate immunity do not contribute to the risk for chronic disseminated candidiasis in adult leukemia patients."

[3].
"FCGR3B polymorphism in three ethnic Chinese populations."

[4].
"[FCGR3B gene frequencies and FCGR3 gene variants in Chinese: a study in 487 Chinese individuals from Zhejiang Province]."

[5].
"Characterization of a new alloantigen (SH) on the human neutrophil Fc gamma receptor IIIb."

[6].
"The human low affinity immunoglobulin G Fc receptor III-A and III-B genes. Molecular characterization of the promoter regions."

[7].
"Fcγ receptor IIIb polymorphism and use of glucocorticoids at baseline are associated with infusion reactions to infliximab in patients with rheumatoid arthritis."

[8].
"FCGR2B gene polymorphism rather than FCGR2A, FCGR3A and FCGR3B is associated with anti-GBM disease in Chinese."

[9].
"FCGR3B copy number variation is not associated with lupus nephritis in a Chinese population."

[10].
"Fcgamma receptor polymorphisms and their association with periodontal disease: a meta-analysis."
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