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FCGR1A (基因名), High affinity immunoglobulin gamma Fc receptor I (蛋白名), fcgr1_human1.
产品名称:

Human FCGR1A/ High affinity immunoglobulin gamma Fc receptor I Recombinant Protein
高亲和力γ免疫球蛋白FC段受体I

货号:

R1578h

商标:
EIAab®
监管等级:
别名:

Fc-gamma RI, Fc-gamma RIA, FcRI, FcgammaRIa, CD64, IgG Fc receptor I, FCG1, FCGR1, IGFR1

序列号:
P12314
来源:
E.coli
种属:
Human
标签:
His
序列:
238-374aa
预估分子量:
15.07 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human FCGR1A Protein
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Human FCGR1A Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human FCGR1A Protein
Recombinant human FCGR1A protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 1q21.2 by HGNC 1q21.2 by Entrez Gene 1q21.2 by Ensembl
FCGR1A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL. Interacts with HCK and LYN.


功能:
High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.


亚细胞位置:
Cell membrane Single-pass type I membrane protein Stabilized at the cell membrane through interaction with FCER1G.


该产品尚未在任何出版物中被引用。

[1].
"Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1."

[2].
"The three genes of the human FCGR1 gene family encoding Fc gamma RI flank the centromere of chromosome 1 at 1p12 and 1q21."

[3].
"Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn."

[4].
"Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI) encode four distinct transcription products."

[5].
"Crystal structure of Fcγ receptor I and its implication in high affinity γ-immunoglobulin binding."

[6].
"Correlation of FCGR3A and EGFR germline polymorphisms with the efficacy of cetuximab in KRAS wild-type metastatic colorectal cancer."

[7].
"Exaggerated neointima formation in human C-reactive protein transgenic mice is IgG Fc receptor type I (Fc gamma RI)-dependent."

[8].
"Early expression of FcgammaRI (CD64) on monocytes of cardiac surgical patients and higher density of monocyte anti-inflammatory scavenger CD163 receptor in "on-pump" patients."

[9].
"Protein 4.1G binds to a unique motif within the Fc gamma RI cytoplasmic tail."

[10].
"Association of interleukin-1 receptor antagonist +2018 gene polymorphism with Japanese chronic periodontitis patients using a novel genotyping method."
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