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FER (基因名), Tyrosine-protein kinase Fer (蛋白名), fer_canfa.
产品名称:

Dog FER/ Tyrosine-protein kinase Fer Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Proto-oncogene c-Fer, p94-Fer

序列号:
Q9TTY2
来源:
E.coli
种属:
Dog
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Dog FER Protein
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Dog FER Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Homotrimer. Interacts with CTNND1, EGFR, FLT3, IRS1, PECAM1, PIK3R1 and PDGFR. Interacts (via SH2 domain) with CTTN. Component of a complex that contains at least FER, CTTN and PTK2/FAK.


功能:
Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell attachment and cell migration. Acts downstream of EGF, PDGFA and PDGFB receptors. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Phosphorylates CTTN, CTNND1, PTK2/FAK, GAB1, PECAM1 and PTPN11.


亚细胞位置:
Cytoplasm Cytoplasm cytoskeleton Cell membrane Peripheral membrane protein Cytoplasmic side Cell projection Cell junction Membrane Peripheral membrane protein Cytoplasmic side Nucleus Cytoplasm cell cortex Associated with the chromatin. Detected on microtubles in polarized and motile vascular endothelial cells. Colocalizes with F-actin at the cell cortex. Colocalizes with PECAM1 and CTNND1 at nascent cell-cell contacts.


该产品尚未在任何出版物中被引用。
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