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GADD45G (基因名), Growth arrest and DNA damage-inducible protein GADD45 gamma (蛋白名), ga45g_human.
产品名称:

Human GADD45G/ Growth arrest and DNA damage-inducible protein GADD45 gamma Recombinant Protein
生长抑制和DNA损伤诱导蛋白GADD45γ

货号:

R2743h

商标:
EIAab®
监管等级:
别名:

Cytokine-responsive protein CR6, DNA damage-inducible transcript 2 protein, DDIT-2, CR6, DDIT2

序列号:
O95257
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human GADD45G Protein
规格 & 价格: cart
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Human GADD45G Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 9q22.2 by HGNC 9q22.2 by Entrez Gene 9q22.2 by Ensembl
GADD45G Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Undergoes concentration-dependent homodimerization, which is required for growth inhibititory activity and enhances interaction with PCNA. Interacts with GADD45GIP1. Interacts with PCNA.


功能:
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK."

[2].
"Molecular cloning, expression, and mapping of a novel human cDNA, GRP17, highly homologous to human gadd45 and murine MyD118."

[3].
"Cytokine response gene 6 induces p21 and regulates both cell growth and arrest."

[4].
"Crystal structure of human Gadd45γ [corrected] reveals an active dimer."

[5].
"A genome-wide association study identifies protein quantitative trait loci (pQTLs)."

[6].
"Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women."

[7].
"A novel pathway involving melanoma differentiation associated gene-7/interleukin-24 mediates nonsteroidal anti-inflammatory drug-induced apoptosis and growth arrest of cancer cells."

[8].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[9].
"CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycle."

[10].
"GADD45gamma, down-regulated in 65% hepatocellular carcinoma (HCC) from 23 chinese patients, inhibits cell growth and induces cell cycle G2/M arrest for hepatoma Hep-G2 cell lines."
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