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GAS6 (基因名), Growth arrest-specific protein 6 (蛋白名), gas6_human.
产品名称:

Human GAS6/ Growth arrest-specific protein 6 Recombinant Protein
生长停滞特异性蛋白6

货号:

R1906h

商标:
EIAab®
监管等级:
别名:

AXL receptor tyrosine kinase ligand, GAS-6, AXLLG

序列号:
Q14393
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant Protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Human GAS6 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 13q34 by HGNC 13q34 by Entrez Gene 13q34 by Ensembl
GAS6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Heterodimer and heterotetramer with AXL.


功能:
(Microbial infection) Can bridges virus envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry by apoptotic mimicry (PubMed:21501828). Plays a role in Dengue cell entry by apoptotic mimicry (PubMed:23084921). Plays a role in Vaccinia virus cell entry by apoptotic mimicry (PubMed:21501828). Plays a role in ebolavirus and marburgvirus cell entry by apoptotic mimicry (PubMed:17005688).


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Human vitamin K-dependent GAS6: gene structure, allelic variation, and association with stroke."

[2].
"The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade."

[3].
"Plasma level of growth arrest-specific 6 (GAS6) protein and genetic variations in the GAS6 gene in patients with acute coronary syndrome."

[4].
"Association of specific haplotypes of GAS6 gene with stroke."

[5].
"Structural basis for Gas6-Axl signalling."

[6].
"The product of a gas6 splice variant allows the release of the domain responsible for Axl tyrosine kinase receptor activation."

[7].
"Identification and tissue expression of a splice variant for the growth arrest-specific gene gas6."

[8].
"Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl."

[9].
"The soluble serum protein Gas6 bridges virion envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entry."

[10].
"Androgen receptor-dependent transactivation of growth arrest-specific gene 6 mediates inhibitory effects of testosterone on vascular calcification."
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