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GABRA2 (基因名), Gamma-aminobutyric acid receptor subunit alpha-2 (蛋白名), gbra2_human.
产品名称:

Human GABRA2/ Gamma-aminobutyric acid receptor subunit alpha-2 Recombinant Protein
γ氨基丁酸受体亚基α2

货号:

R0464h

商标:
EIAab®
监管等级:
别名:

GABA(A) receptor subunit alpha-2

序列号:
P47869
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cell Biology
Human GABRA2 Protein
规格 & 价格: cart
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Human GABRA2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 4p12 by HGNC 4p12 by Entrez Gene 4p12 by Ensembl
GABRA2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with UBQLN1. Interacts with KIF21B.


功能:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.


亚细胞位置:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein Cytoplasmic vesicle membrane


该产品尚未在任何出版物中被引用。

[1].
"GABA-A2 receptor subunit gene (GABRA2) polymorphisms and risk for alcohol dependence."

[2].
"Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations."

[3].
"Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype."

[4].
"Association study of 182 candidate genes in anorexia nervosa."

[5].
"Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder."

[6].
"Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?"

[7].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[8].
"Analysis of extreme drinking in patients with alcohol dependence using Pareto regression."

[9].
"The influence of GABRA2, childhood trauma, and their interaction on alcohol, heroin, and cocaine dependence."

[10].
"Test of association between GABRA2 (SNP rs279871) and adolescent conduct/alcohol use disorders utilizing a sample of clinic referred youth with serious substance and conduct problems, controls and available first degree relatives."
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