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GABRA3 (基因名), Gamma-aminobutyric acid receptor subunit alpha-3 (蛋白名), gbra3_human.
产品名称:

Human GABRA3/ Gamma-aminobutyric acid receptor subunit alpha-3 Recombinant Protein
-氨基丁酸受体亚基-3

货号:

R0470h

商标:
EIAab®
监管等级:
别名:

GABA(A) receptor subunit alpha-3

序列号:
P34903
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human GABRA3 Protein
规格 & 价格: cart
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Human GABRA3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: Xq28 by HGNC Xq28 by Entrez Gene Xq28 by Ensembl
GABRA3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Binds UBQLN1 (By similarity). Interacts with GPHN (PubMed:26613940).


功能:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.


亚细胞位置:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Association study between GABA receptor genes and anxiety spectrum disorders."

[2].
"Pathway-based association analysis of genome-wide screening data suggest that genes associated with the gamma-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced, treatment-resistant tardive dyskinesia."

[3].
"Association of genetic variants in GABRA3 gene and thyrotoxic hypokalaemic periodic paralysis in Thai population."

[4].
"Lack of association between polymorphic variations in the alpha 3 subunit GABA receptor gene (GABRA3) and suicide attempts."

[5].
"Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy."
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