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GDF11 (基因名), Growth/differentiation factor 11 (蛋白名), gdf11_human.
产品名称:

Human GDF11/ Growth/differentiation factor 11 Recombinant Protein
生长分化因子11

货号:

R0343h

商标:
EIAab®
监管等级:
别名:

Bone morphogenetic protein 11, BMP-11, GDF-11, BMP11

序列号:
O95390
来源:
E.coli
种属:
Human
标签:
His
序列:
299-407aa
预估分子量:
11.99 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Signal Transduction
Human GDF11 Protein
规格 & 价格: cart
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Human GDF11 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human GDF11 Protein
Recombinant human GDF11 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 12q13.2 by HGNC 12q13.2 by Entrez Gene 12q13.2 by Ensembl
GDF11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer; disulfide-linked.


功能:
Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.


亚细胞位置:
Secreted



[1].
"GDF11 forms a bone morphogenetic protein 1-activated latent complex that can modulate nerve growth factor-induced differentiation of PC12 cells."

[2].
"Structural basis for potency differences between GDF8 and GDF11."

[3].
"Crystal structure of human GDF11."

[4].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."

[5].
"Clinical significance of growth differentiation factor 11 in colorectal cancer."

[6].
"A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos."

[7].
"Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11."

[8].
"Physical inactivity is associated with decreased growth differentiation factor 11 in chronic obstructive pulmonary disease."

[9].
"Reduced expression of growth differentiation factor 11 promoted the progression of chronic obstructive pulmonary disease by activating the AKT signaling pathway."

[10].
"Architecture of the human interactome defines protein communities and disease networks."
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