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HIST1H4A (基因名), Histone H4 (蛋白名), h4_human.
产品名称:

Human HIST1H4A/ Histone H4 Recombinant Protein
组蛋白H4

货号:

R1485h

商标:
EIAab®
监管等级:
别名:

H4/A, H4FA

序列号:
P62805
来源:
E.coli
种属:
Human
标签:
His
序列:
1-103aa
预估分子量:
11.33 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Epigenetics
  • Human HIST1H4A Protein
  • Human HIST1H4A Protein
  • Human HIST1H4A Protein
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Human HIST1H4A Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
The sequence analysis of human HIST1H4A protein including hydrophilcity, hydrophobicity and antigenicity.
Human HIST1H4A Protein
Recombinant human HIST1H4A protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 6p22.2 by HGNC 6p22.2 by Entrez Gene 6p22.2 by Ensembl
HIST1H4A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.


功能:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.


亚细胞位置:
Nucleus Chromosome


该产品尚未在任何出版物中被引用。

[1].
"The human and mouse replication-dependent histone genes."

[2].
"Human histone gene organization: nonregular arrangement within a large cluster."

[3].
"BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response."

[4].
"SET8 recognizes the sequence RHRK20VLRDN within the N terminus of histone H4 and mono-methylates lysine 20."

[5].
"Histone sumoylation is associated with transcriptional repression."

[6].
"Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor."

[7].
"The human histone gene cluster at the D6S105 locus."

[8].
"Protein-DNA interactions in vivo upstream of a cell cycle-regulated human H4 histone gene."

[9].
"Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease."

[10].
"A Chemical Proteomics Approach to Reveal Direct Protein-Protein Interactions in Living Cells."
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