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HBP1 (基因名), HMG box-containing protein 1 (蛋白名), hbp1_human.
产品名称:

Human HBP1/ HMG box-containing protein 1 Recombinant Protein
HMG盒蛋白1

货号:

R6776h

商标:
EIAab®
监管等级:
别名:

HMG box transcription factor 1, High mobility group box transcription factor 1

序列号:
O60381
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human HBP1 Protein
规格 & 价格: cart
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Human HBP1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 7q22.3 by HGNC 7q22.3 by Entrez Gene 7q22.3 by Ensembl
HBP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.


功能:
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。

[1].
"Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1."

[2].
"Human HMG box transcription factor HBP1: a role in hCD2 LCR function."

[3].
"HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family."

[4].
"The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation."

[5].
"Macrophage migration inhibitory factor is a direct target of HBP1-mediated transcriptional repression that is overexpressed in prostate cancer."

[6].
"Alterations of the HBP1 transcriptional repressor are associated with invasive breast cancer."

[7].
"Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells."

[8].
"Human high mobility group box transcription factor 1 affects thymocyte development and transgene variegation."

[9].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[10].
"HBP1 repression of the p47phox gene: cell cycle regulation via the NADPH oxidase."
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